Non-prescription drugs (OTC) is a special group of children. Compared with the adult children of various tissues and organs of the body is not yet mature, more susceptible to adverse drug reactions ......
Not all of them will happen after the medication allergy reaction, eruption will occur in individuals with allergies. General incidence of eruption is not immediately apparent, but has a latency period. The first medication often do not cause a rash, but has led to a pathogenic organism in the state, the average period of 7-10 days, and then a second time when the same drug, the rapid emergence of response within 24 hours. Even apart for a long time can cause relapse. The most common cause of drug allergy in children are four kinds: (1) anti-inflammatory drugs; such as APC, Aru films, Bamir and other aspirin-containing oral antipyretics. Antongding intramuscular injection can cause eruption, but more serious. (2) sulfa drugs; such as cotrimoxazole. (3) penicillin antibiotics; such as oral An Bilin, intramuscular injection of penicillin, ampicillin, such as intravenous use. (4) a variety of other vaccines and some herbs can cause eruption. Common pediatric medicine clinics are the following: fixity erythema: fat in the skin around the mouth, anus and external genitalia are also common. Rash special form, for easy identification. Features bright red or purple edema, erythema, were round or oval, clear boundaries. Aspirin, APC, Aru tablets, cotrimoxazole and so easy to cause such about rash. Erythematous rash type: the performance of the whole body, symmetry distributed a large number of small pimple-like red brown, or red patches miliary size form like measles, scarlet fever style, with mild to moderate fever. Such eruption to penicillin-type drugs most commonly, such as ampicillin, An Bilin and so on. Urticaria: the performance of systemic wheal sizes, flat elevated, irregular, accompanied by significant itching, some children have a fever, fatigue, joint pain and abdominal pain and other symptoms. Children with measles and other common drugs causing force penicillin, dysentery long, tetanus antitoxin and rabies vaccine. Epidermolysis bullosa type: drug eruption is the most serious type, is also one of the most serious skin diseases in children. General acute onset, rapid progression, a serious condition, the treatment less often can lead to death. Rash onset in children often face, neck and chest, as miliary to mung bean size dark red to dark red stain films, quickly fused into blockbusters. 1-2 days rash development body, the central part of the erythema appear small water, the patients with severe symptoms of systemic poisoning children, accompanied by high fever, lethargy and heart and liver, kidney and other internal organs damage. Suffering from epidermolysis bullosa eruption of the children, if emergency treatment is not timely, may be due to secondary infection caused by sepsis, pneumonia , renal failure or cerebral hemorrhage and death. This type of eruption is more common allergenic drugs Antongding, Lumina and so on.
