Diagnosis:
1. Fever, infection and general malaise and other prodromal symptoms.
2. Skin occur in batches, symmetrical distribution, sizes, higher than the leather and the pressure of not fade papular purpura .
3. Some patients accompanied by abdominal and joint pain, and urinary abnormalities.
4. Platelet count, bleeding and bone marrow function properly.
5. Excluding other bleeding disorders.
Diagnostic criteria
1 near future viruses, bacteria, parasites, infections or food, drug and other allergies history.
2. recurring skin purpura, may have abdominal pain, blood in the stool (abdominal), joint pain (joint type) and hematuria, edema (kidney type).
3 purpura symmetrically distributed in the extensor limbs and buttocks, may have rash, urticaria measles , angioneurotic edema, as well as small blood blisters, necrosis and ulceration may have left the pigment calm after several episodes.
4 normal blood and bone marrow, occasionally increased eosinophils.
5 If renal involvement, visible red blood cells in urine, protein and granular casts, few patients can become chronic nephritis , and even the development of uremia .
6 bleeding time, clotting time, platelet count, blood clot contraction time is normal. Capillary fragility test was positive.
Laboratory tests
1. Beam arm about half of the patients test positive.
2. WBC light to moderate increased eosinophils may be associated with increased cell. Out, clotting time, platelet count, clot contraction time and the clotting factor activity were normal. Most patients with mild ESR faster.
3. Kidney involvement can occur in urine protein, red blood cells or casts, renal dysfunction, blood urea nitrogen and creatinine were increased.
4. There parasite infection, it can detect eggs. Abdominal who vomit and fecal occult blood can be positive.
5. Anti-"0" can be increased. About half of patients with elevated serum IgA.
6. Bone marrow is normal.
Differential diagnosis:
Atypical cases, especially before purpura appear that there is abdominal pain, bloody diarrhea, joint pain and urinary changes should be identified with the following diseases.
1. Simple skin type and thrombocytopenic purpura differentiated: the latter mainly for skin and mucous membrane bleeding, irregular distribution, no joints and nephritis and other symptoms (except those caused by connective tissue disease), prolonged bleeding time, poor clot contraction, platelet count reduce the abnormal bone marrow megakaryocytes.
2. Articulated with rheumatic fever differentiated: If joint pain occurs before purpura and accompanied by fever, rheumatic fever need and phase identification. The latter often ring erythema or subcutaneous nodules around the joint symptoms appear. ESR, anti-"0" and more positive.
3. To be associated with acute abdominal appendicitis , necrotizing enterocolitis differentiated: acute appendicitis abdominal pain point for Maxwell persistent pain, aggravated sexual. Local muscle tension, tenderness and rebound tenderness, peripheral blood leukocytes and neutrophils increased. Systemic necrotizing enteritis patients with severe symptoms, accompanied by bloating, tenderness and rebound tenderness, peripheral blood leukocytes and neutrophils increased, there is pus in the stool and red blood cells.
